SCHEMBL27653174

SCHEMBL27653174

ON1NNc2ccc(Cl)cc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.35
DAO P14920 1/20 0.33
AADAT Q8N5Z0 1/20 0.33
TGM2 P21980 1/20 0.32
CES1 P23141 1/20 0.32
HTR2C P28335 1/20 0.32
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
MYC P01106 1/20 0.32
IDO1 P14902 1/20 0.32
AHR P35869 1/20 0.32
TSHR P16473 2/20 0.31
HSD17B10 Q99714 2/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NOTUM Q6P988 1/20 0.31
CHEK1 O14757 1/20 0.31
LIMK1 P53667 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27653271 0.84 DAO (0.33) DAOAADATCES1CA12CA9
SCHEMBL27673095 0.71 MAPT (0.39) ALDH1A1TDP1MEN1GAAKMT2A
SCHEMBL10432082 0.65 PTPN1 (0.33) PTPN1DAOAADATTGM2CES1
SCHEMBL27673113 0.64 DAO (0.33) DAOAADATHSD17B10ALDH1A1CYP3A4
SCHEMBL27681806 0.63 HSD17B10 (0.37) DAOAADATMYCIDO1TSHR
SCHEMBL22431926 0.60 CHEK1 (0.41) TGM2CES1IDO1AHRTSHR
SCHEMBL884143 0.58 AHR (0.37) PTPN1TGM2CES1HTR2CAHR
SCHEMBL13868943 0.58 CHEK1 (0.59) TGM2CES1HTR2CCA12CA9
SCHEMBL13868946 0.58 CHEK1 (0.59) TGM2CES1HTR2CCA12CA9
SCHEMBL23253790 0.57 PTPN1 (0.45) PTPN1TGM2CES1HTR2CIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100528937-C Method for producing carbonyl rest-containing organosilicon compounds WACKER CHEMIE GMBH (DE) 2009-08-19 CN disclosed
CN-1906230-A Method for producing carbonyl group-containing organosilicon compound WACKER CHEMIE GMBH (DE) 2007-01-31 CN disclosed