SCHEMBL27673113

SCHEMBL27673113

Cc1ccc2c(c1)NNN2O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.33
AADAT Q8N5Z0 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
TRPA1 O75762 1/20 0.32
ALDH1A1 P00352 3/20 0.32
NOTUM Q6P988 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CA2 P00918 1/20 0.31
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP1A2 P05177 3/20 0.31
CYP2A6 P11509 2/20 0.31
HSD17B10 Q99714 2/20 0.31
GAA P10253 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MAPT P10636 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921005 0.78 ACHE (0.33) ALDH1A1NPSR1TDP1CYP1A2CYP2A6
SCHEMBL27653271 0.76 DAO (0.33) DAOAADATLMNAALDH1A1NOTUM
SCHEMBL19848718 0.72 NOTUM (0.33) LMNAALDH1A1NOTUMGAASMN1; SMN2
SCHEMBL4594319 0.70 GAA (0.36) GAASMN1; SMN2
SCHEMBL7922386 0.65 ROS1 (0.34) NPC1LMNARAB9AALDH1A1TDP1
SCHEMBL6157962 0.64 LMNA (0.43) AADATNPC1LMNARAB9ATRPA1
SCHEMBL27673095 0.63 MAPT (0.39) NPC1LMNARAB9AALDH1A1TDP1
SCHEMBL10238719 0.60 HDAC1 (0.47) ALDH1A1HSD17B10GAAMAPTCYP3A4
SCHEMBL8342113 0.60 CYP1A2 (0.39) LMNATRPA1ALDH1A1CA2TP53
SCHEMBL20888788 0.59 ATM (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100528937-C Method for producing carbonyl rest-containing organosilicon compounds WACKER CHEMIE GMBH (DE) 2009-08-19 CN disclosed
CN-1906230-A Method for producing carbonyl group-containing organosilicon compound WACKER CHEMIE GMBH (DE) 2007-01-31 CN disclosed