Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CFTR | P13569 | 4/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 8/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803162 | 0.85 | ACHE (0.42) | KDM4EALDH1A1CFTRABL1HSD17B10 | |
| Hydrochloric Acid SCHEMBL484839 | 0.84 | ACHE (0.44) | ALDH1A1CFTRABL1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL484838 | 0.84 | ACHE (0.44) | ALDH1A1CFTRABL1HSD17B10HPGD | |
| SCHEMBL803251 | 0.82 | ACHE (0.42) | ALDH1A1CFTRABL1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL785262 | 0.81 | ACHE (0.44) | ALDH1A1CFTRABL1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL785261 | 0.81 | ACHE (0.44) | ALDH1A1CFTRABL1HSD17B10HPGD | |
| SCHEMBL2479188 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1CFTRABL1GAA | |
| SCHEMBL13131186 | 0.77 | ACHE (0.45) | ALDH1A1CFTRABL1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL15226690 | 0.76 | ACHE (0.44) | ALDH1A1CFTRHSD17B10HPGDACHE | |
| Hydrochloric Acid SCHEMBL2816232 | 0.76 | ACHE (0.44) | ALDH1A1CFTRHSD17B10HPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972932-B | Compounds for the treatment of dyslipidemia | LILLY CO ELI | 2011-06-29 | — | — | CN | disclosed |
| CN-1972932-A | Compounds and methods for treating dyslipidemia | LILLY CO ELI (US) | 2007-05-30 | — | — | CN | disclosed |
| CN-1863778-A | Compounds and methods for treating dyslipidemia | LILLY CO ELI (US) | 2006-11-15 | — | — | CN | disclosed |