Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 9/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.53 |
| ▸ | PYGL | P06737 | 4/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | BCL6 | P41182 | 1/20 | 0.43 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655429 | 0.89 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL2199211 | 0.87 | MAPK13 (0.63) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL27634619 | 0.87 | MAPK13 (0.44) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL27655424 | 0.86 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL27655413 | 0.83 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL27655411 | 0.82 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL2200872 | 0.80 | MAPK14 (0.62) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL2198601 | 0.79 | MAPK13 (0.63) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL2203119 | 0.78 | MAPK14 (0.54) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL2199405 | 0.77 | MAPK14 (0.61) | MAPK13MAPK12MAPK11MAPK14BCL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1826310-B | Novel aminobenzophenone compounds | LEO PHARMA AS | 2010-07-21 | — | — | CN | disclosed |
| CN-1826310-A | Novel aminobenzophenone compounds | LEO PHARMA AS (DK) | 2006-08-30 | — | — | CN | disclosed |