Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 11/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196661 | 0.89 | MAPK14 (0.56) | MAPK13MAPK12MAPK11MAPK14AKR1C3 | |
| SCHEMBL27634619 | 0.84 | MAPK13 (0.44) | MAPK13MAPK12MAPK11MAPK14AKR1C3 | |
| SCHEMBL27655424 | 0.84 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14AKR1C3 | |
| SCHEMBL27655412 | 0.83 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL27655429 | 0.82 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL27655411 | 0.82 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14AKR1C3 | |
| SCHEMBL2198124 | 0.81 | MAPK14 (0.56) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL2198749 | 0.79 | MAPK14 (0.54) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL1907229 | 0.79 | MAPK14 (0.76) | MAPK13MAPK12MAPK11MAPK14AKR1C3 | |
| SCHEMBL2196285 | 0.77 | MAPK14 (0.49) | MAPK13MAPK12MAPK11MAPK14MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1826310-B | Novel aminobenzophenone compounds | LEO PHARMA AS | 2010-07-21 | — | — | CN | disclosed |
| CN-1826310-A | Novel aminobenzophenone compounds | LEO PHARMA AS (DK) | 2006-08-30 | — | — | CN | disclosed |