Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665251 | 0.81 | GAA (0.48) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL665708 | 0.81 | GAA (0.48) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL665796 | 0.81 | GAA (0.48) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL18975217 | 0.78 | DRD2 (0.42) | MEN1KMT2AL3MBTL1ALDH1A1TP53 | |
| SCHEMBL763968 | 0.78 | DRD2 (0.42) | MEN1KMT2AL3MBTL1ALDH1A1TP53 | |
| SCHEMBL27655695 | 0.77 | MEN1 (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4373095 | 0.77 | — | — | |
| SCHEMBL1504812 | 0.77 | — | — | |
| SCHEMBL1829243 | 0.77 | — | — | |
| SCHEMBL4388841 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1890238-A | Hydronopol derivatives as agonists on human ORL1 receptors | SOLVAY PHARM GMBH (DE) | 2007-01-03 | — | — | CN | disclosed |