Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21631824 | 1.00 | FOLH1 (0.50) | FOLH1TDP1RNPEPSMN1; SMN2SLC22A6 | |
| SCHEMBL637786 | 0.97 | FOLH1 (0.52) | FOLH1TDP1RNPEPSMN1; SMN2SLC22A6 | |
| SCHEMBL7899825 | 0.97 | FOLH1 (0.52) | FOLH1TDP1RNPEPSMN1; SMN2SLC22A6 | |
| SCHEMBL2103664 | 0.94 | — | — | |
| SCHEMBL133541 | 0.94 | — | — | |
| SCHEMBL637801 | 0.92 | FOLH1 (0.52) | FOLH1TDP1RNPEPSMN1; SMN2SLC22A6 | |
| Lithium SCHEMBL31092059 | 0.92 | FOLH1 (0.52) | FOLH1TDP1RNPEPSMN1; SMN2SLC22A6 | |
| SCHEMBL1546190 | 0.92 | FOLH1 (0.52) | FOLH1TDP1RNPEPSMN1; SMN2SLC22A6 | |
| Water SCHEMBL30605181 | 0.92 | FOLH1 (0.52) | FOLH1TDP1RNPEPSMN1; SMN2SLC22A6 | |
| SCHEMBL11582606 | 0.92 | FOLH1 (0.52) | FOLH1TDP1RNPEPSMN1; SMN2SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104804089-A | Il-1 binding proteins | ABBVIE INC | 2015-07-29 | — | — | CN | disclosed |
| CN-103025758-A | IL-1 binding proteins | ABBOTT LAB | 2013-04-03 | — | — | CN | disclosed |
| CN-101381366-B | Benzimidazole derivative and its use as a ii receptor antagonist | TAKEDA CHEMICAL INDUSTRIES LTD | 2011-06-15 | — | — | CN | disclosed |
| CN-100503605-C | Benzimidazole derivatives and their use as AII receptor antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2009-06-24 | — | — | CN | disclosed |
| CN-101381366-A | Benzimidazole derivative and its use as a ii receptor antagonist | TAKEDA PHARMACEUTICAL (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-1946717-A | Benzimidazole derivatives and their use as AII receptor antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2007-04-11 | — | — | CN | disclosed |