Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 18/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3560197 | 0.88 | MLNR (0.48) | MLNRCYP3A4CCR1 | |
| SCHEMBL2767737 | 0.86 | MLNR (0.69) | MLNRCCR1MGLL | |
| SCHEMBL2768337 | 0.86 | MLNR (0.57) | MLNRCCR1MGLL | |
| SCHEMBL2767766 | 0.84 | MLNR (0.72) | MLNRCCR1MGLL | |
| SCHEMBL2767872 | 0.84 | MLNR (0.72) | MLNRCCR1MGLL | |
| SCHEMBL2766215 | 0.84 | MLNR (0.75) | MLNR | |
| SCHEMBL2766758 | 0.83 | MLNR (0.58) | MLNRCCR1MGLL | |
| SCHEMBL2767685 | 0.82 | MLNR (0.72) | MLNRCCR1 | |
| SCHEMBL2765987 | 0.82 | MLNR (0.73) | MLNRCCR1 | |
| SCHEMBL2767564 | 0.82 | MLNR (0.73) | MLNRCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041093-B1 | PIPERAZINYL DERIVATIVES USEFUL IN THE TREATMENT OF GPR38 RECEPTOR MEDIATED DISEASES | GLAXO GROUP LTD (GB) | 2010-04-21 | — | — | EP | disclosed |