Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 12/20 | 0.57 |
| ▸ | CCR1 | P32246 | 5/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | FPR3 | P25089 | 1/20 | 0.45 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13404709 | 0.89 | MLNR (0.54) | MLNRCCR1MGLLFPR3GPR65 | |
| SCHEMBL2766234 | 0.88 | MLNR (0.74) | MLNRCCR1MGLL | |
| SCHEMBL2765627 | 0.88 | MLNR (0.61) | MLNRCCR1MGLL | |
| SCHEMBL2765663 | 0.86 | MLNR (0.52) | MLNRCCR1MGLL | |
| SCHEMBL2767326 | 0.85 | MLNR (0.62) | MLNRCCR1MGLL | |
| SCHEMBL2766923 | 0.84 | MLNR (0.77) | MLNR | |
| SCHEMBL2767206 | 0.84 | MLNR (0.61) | MLNRCCR1MGLL | |
| SCHEMBL3567849 | 0.83 | MLNR (0.49) | MLNRCCR1MGLL | |
| SCHEMBL2767002 | 0.82 | MLNR (0.61) | MLNRCCR1 | |
| SCHEMBL2765421 | 0.81 | MLNR (0.73) | MLNRCCR1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041093-B1 | PIPERAZINYL DERIVATIVES USEFUL IN THE TREATMENT OF GPR38 RECEPTOR MEDIATED DISEASES | GLAXO GROUP LTD (GB) | 2010-04-21 | — | — | EP | disclosed |