SCHEMBL27656744

SCHEMBL27656744

C1CNC(OC2CCCN2)C1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
MEN1 O00255 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27725254 0.88 CYP2D6 (0.35) MEN1KMT2A
SCHEMBL11942459 0.78
SCHEMBL13686684 0.78
SCHEMBL8245418 0.78
SCHEMBL6280246 0.77
SCHEMBL1298622 0.77
SCHEMBL17904505 0.77
SCHEMBL16453949 0.77
SCHEMBL31472606 0.77
SCHEMBL27731852 0.73 KMT2A (0.40) NOS2NOS3NOS1MEN1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104379744-A Single-stranded nucleic acid molecule for controlling gene expression having delivery function BONAC CORP 2015-02-25 CN disclosed
CN-102070451-A Methods and compounds producing dipeptidyl peptidase IV inhibitors and intermediates thereof BRISTOL MYERS SQUIBB CO 2011-05-25 CN disclosed
CN-101108809-B 1- (alkylaminoalkyl-pyrrolidine-/piperidinyl) -2, 2-diphenylacetamide derivatives as muscarinic receptor antagonists THERAVANCE INC 2010-07-14 CN disclosed
CN-101108809-A 1- (alkylaminoalkyl-pyrrolidine-/piperidinyl) -2, 2-diphenylacetamide derivatives as muscarinic receptor antagonists THERAVANCE INC (US) 2008-01-23 CN disclosed
CN-1805927-A 1- (alkylaminoalkyl-pyrrolidine-/piperidinyl) -2, 2-diphenylacetamide derivatives as muscarinic receptor antagonists THERAVANCE INC (US) 2006-07-19 CN disclosed