⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298622 | 1.00 | — | — | |
| SCHEMBL16453949 | 1.00 | — | — | |
| SCHEMBL16453950 | 0.92 | — | — | |
| SCHEMBL899412 | 0.92 | — | — | |
| SCHEMBL1484812 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL28032357 | 0.90 | — | — | |
| SCHEMBL7346006 | 0.90 | — | — | |
| SCHEMBL11728861 | 0.90 | SLC6A3 (0.33) | — | |
| Hydrochloric Acid SCHEMBL11644251 | 0.90 | — | — | |
| SCHEMBL9347890 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207482-A | Pyrimidine derivatives for treating cancer | 默克专利股份公司 | 2017-09-26 | — | — | CN | claimed |
| CN-104684893-A | Asymmetric auxiliary group | CHIRALGEN LTD | 2015-06-03 | — | — | CN | claimed |
| CN-109265400-A | Arginine methyltransferase inhibitor and application thereof | EPIZYME股份有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-108883099-A | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | 石全 | 2018-11-23 | — | — | CN | disclosed |
| CN-104876955-B | Arginase inhibitor and its treatment use | 马尔斯公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-104903320-B | Nitrogen-containing heterocycle compound or its salt | 富士胶片株式会社 | 2018-11-13 | — | — | CN | disclosed |
| CN-105339351-B | Arginine methyltransferase inhibitors and uses thereof | EPIZYME股份有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-108383858-A | Treat the derivative of the imidazo thiadiazoles and Imidazopyrazines of platelet aggregation | 百时美施贵宝公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-105593232-B | Benzoxazoloxazinone compounds as coagulation factor Xa inhibitors | 华北制药集团新药研究开发有限责任公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-108112251-A | NRF2 conditioning agents | 葛兰素史克知识产权发展有限公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-104364246-B | Piperidine derivatives useful as GPR119 agonists | 株式会社钟根堂 | 2018-05-22 | — | — | CN | disclosed |
| CN-1607951-A | Quinoline derivatives as neuropeptide y antagonists | HOFFMANN LA ROCHE (CH) | 2005-04-20 | — | — | CN | disclosed |
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |
| CN-1146542-C | Benzamide derivatives and their use as cytokine inhibitors | — | 2004-04-21 | — | — | CN | disclosed |
| CN-1391562-A | Quinazoline derivatives as medicaments | ASTRAZENECA AB (SE) | 2003-01-15 | — | — | CN | disclosed |
| CN-1319092-A | Benzamide derivatives and their use as cytokine inhibitors | ASTRAZENECA AB (SE) | 2001-10-24 | — | — | CN | disclosed |
| CN-1276727-A | Growth hormone secretagogues | LILLY CO ELI (US) | 2000-12-13 | — | — | CN | disclosed |
| CN-1027262-C | Benzazepine and benzothiazepine derivatives | E R SQUID & SONS INC (US) | 1995-01-04 | — | — | CN | disclosed |
| CN-1047673-A | Anticonvulsants | PFIZER (US) | 1990-12-12 | — | — | CN | disclosed |
| CN-1039585-A | BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | SQUIBB & SONS INC (US) | 1990-02-14 | — | — | CN | disclosed |