Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 12/20 | 0.47 |
| ▸ | CCKAR | P32238 | 5/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1885909 | 0.89 | CCKBR (0.59) | CCKBRCCKARNR1I2SCN1ASCN1B | |
| SCHEMBL1885912 | 0.89 | CCKBR (0.59) | CCKBRCCKARNR1I2SCN1ASCN1B | |
| SCHEMBL1382499 | 0.88 | CCKBR (0.50) | CCKBRCCKARLMNAESR1 | |
| SCHEMBL1884675 | 0.87 | CCKBR (0.57) | CCKBRCCKARPKLRLMNAESR1 | |
| SCHEMBL1884672 | 0.87 | CCKBR (0.57) | CCKBRCCKARPKLRLMNAESR1 | |
| SCHEMBL1886229 | 0.87 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL1886233 | 0.87 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL1885769 | 0.83 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL1885772 | 0.83 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL31618389 | 0.83 | CCKBR (0.61) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1863781-A | 2- (quinoxalin-5-ylsulfonamido) -benzamide compounds as cholecystokinin 2 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2006-11-15 | — | — | CN | claimed |
| CN-1863781-A | 2- (quinoxalin-5-ylsulfonamido) -benzamide compounds as cholecystokinin 2 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2006-11-15 | — | — | CN | disclosed |
| CN-1863782-A | 2-(quinoxalin-5-ylsulfonylamino)-benzamide compounds as cck2 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2006-11-15 | — | — | CN | disclosed |