Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | NEK2 | P51955 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.45 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2764392 | 0.88 | PDE4A (0.47) | SLC16A3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2764448 | 0.87 | P2RX7 (0.47) | SLC16A3PDE4BALDH1A1HSD17B10HPGD | |
| SCHEMBL2763745 | 0.85 | BCHE (0.49) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL2766860 | 0.82 | SLC29A1 (0.50) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL2225688 | 0.82 | SLC16A3 (0.59) | SLC16A3ALDH1A1SLC16A1MCTS1LMNA | |
| SCHEMBL2766939 | 0.81 | FYN (0.38) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL2764186 | 0.78 | FYN (0.40) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL2765141 | 0.78 | TDP1 (0.54) | ALDH1A1HSD17B10USP2HPGDMAPT | |
| SCHEMBL2764588 | 0.77 | P2RX7 (0.47) | SLC16A3PDE4BALDH1A1HSD17B10HPGD | |
| SCHEMBL3603031 | 0.74 | PDE4B (0.45) | SLC16A3PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400515-B1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | KOWA CO (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-1400515-A1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | Kowa Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6472386-B1 | Cyclic diamine compound with 5-membered ring groups | KOWA CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |