Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | BID | P55957 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.49 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.49 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.49 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | IAPP | P10997 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL21359906 | 0.94 | HTR1A (0.62) | AKR1B1HTR1ATAAR1HSPA5TSHR | |
| SCHEMBL51747 | 0.91 | HTR1A (0.64) | AKR1B1HTR1ATAAR1HSPA5TSHR | |
| SCHEMBL30595395 | 0.91 | HTR1A (0.64) | AKR1B1HTR1ATAAR1HSPA5TSHR | |
| Formaldehyde SCHEMBL6472705 | 0.89 | HTR1A (0.58) | AKR1B1HTR1ATAAR1HSPA5TSHR | |
| SCHEMBL10747568 | 0.89 | HTR1A (0.58) | AKR1B1HTR1ATAAR1HSPA5TSHR | |
| Hydrogen Sulfide SCHEMBL11212668 | 0.89 | HTR1A (0.62) | AKR1B1HTR1ATAAR1HSPA5TSHR | |
| SCHEMBL27567998 | 0.89 | HTR1A (0.62) | AKR1B1HTR1ATAAR1HSPA5TSHR | |
| Water SCHEMBL28808882 | 0.89 | HTR1A (0.62) | AKR1B1HTR1ATAAR1HSPA5TSHR | |
| SCHEMBL28362117 | 0.89 | HTR1A (0.62) | AKR1B1HTR1ATAAR1HSPA5TSHR | |
| Butane SCHEMBL27313193 | 0.89 | HTR1A (0.62) | AKR1B1HTR1ATAAR1HSPA5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113992118-A | Device with photovoltaic power generation and friction power generation functions | 苏州腾晖光伏技术有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-1935574-A | Base for trolley, manufacture method thereof and trolley | TAKANORI CORP (JP) | 2007-03-28 | — | — | CN | disclosed |