Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GPR183 | P32249 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | BCR | P11274 | 2/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16809564 | 0.87 | CHRNA7 (0.64) | HPGDPOLBCA12CA1CA2 | |
| SCHEMBL27658238 | 0.82 | HPGD (0.57) | HPGDPOLBCA12CA1CA2 | |
| SCHEMBL4386969 | 0.80 | HRH3 (0.64) | HPGDPOLBCA12CA1CA2 | |
| SCHEMBL578679 | 0.78 | POLB (0.87) | HPGDPOLBCA12CA1CA2 | |
| SCHEMBL12621027 | 0.78 | POLB (0.87) | HPGDPOLBCA12CA1CA2 | |
| SCHEMBL2646094 | 0.78 | HPGD (0.70) | HPGDPOLBCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL27606633 | 0.77 | POLB (0.84) | HPGDPOLBCA12CA1CA2 | |
| SCHEMBL28067455 | 0.76 | HPGD (0.72) | HPGDPOLBCA12CA1CA2 | |
| SCHEMBL971083 | 0.76 | HPGD (1.00) | HPGDPOLBCA12CA1CA2 | |
| SCHEMBL644199 | 0.76 | HPGD (0.92) | HPGDPOLBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1926127-A | Novel 2-heteroaryl substituted benzimidazole derivatives | BANYU PHARMA CO LTD (JP) | 2007-03-07 | — | — | CN | disclosed |