Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27678380 | 0.87 | MERTK (0.44) | MEN1PKMKMT2ATOP2AMAPT | |
| SCHEMBL5510251 | 0.83 | TOP2A (0.48) | MEN1PKMKMT2ATOP2AMAPT | |
| SCHEMBL5510249 | 0.78 | MEN1 (0.46) | MEN1PKMKMT2ATOP2AMAPT | |
| SCHEMBL17450237 | 0.77 | MEN1 (0.49) | MEN1PKMKMT2A | |
| SCHEMBL5506586 | 0.76 | KMT2A (0.76) | MEN1PKMKMT2AMAPTNPSR1 | |
| SCHEMBL5501524 | 0.76 | KMT2A (0.74) | MEN1PKMKMT2AMAPTNPSR1 | |
| SCHEMBL5505918 | 0.73 | KMT2A (0.77) | MEN1PKMKMT2AMAPTNPSR1 | |
| SCHEMBL5501700 | 0.73 | TOP2A (0.46) | MEN1PKMKMT2ATOP2AMAPT | |
| SCHEMBL530058 | 0.71 | KMT2A (0.50) | MEN1PKMKMT2AKDM4E | |
| SCHEMBL2045638 | 0.70 | KMT2A (0.79) | MEN1PKMKMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1968928-A | Heterocyclic derivatives for treatment of hyperlipidemia and related diseases | AVANIR PHARMACEUTICALS (US) | 2007-05-23 | — | — | CN | disclosed |