SCHEMBL27658914

SCHEMBL27658914

O=C(NC(Cc1ccc(OCc2ccccc2)cc1)C(=O)O)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR132 Q9UNW8 3/20 0.77
PTPN1 P18031 4/20 0.67
PPARG P37231 3/20 0.67
GPR34 Q9UPC5 4/20 0.65
ITGB3 P05106 1/20 0.65
ITGA2B P08514 1/20 0.65
MME P08473 1/20 0.63
ACE P12821 1/20 0.63
CPA1 P15085 1/20 0.63
ACE2 Q9BYF1 1/20 0.63
GAA P10253 1/20 0.62
RAB9A P51151 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1123232 1.00 GPR132 (0.77) GPR132PTPN1PPARGGPR34ITGB3
SCHEMBL1123033 1.00 GPR132 (0.77) GPR132PTPN1PPARGGPR34ITGB3
SCHEMBL1123299 1.00 GPR132 (0.77) GPR132PTPN1PPARGGPR34ITGB3
SCHEMBL1122757 0.99 GPR132 (0.78) GPR132PTPN1PPARGGPR34ITGB3
SCHEMBL6182299 0.97 GPR132 (0.77) GPR132PTPN1PPARGGPR34ITGB3
SCHEMBL27871431 0.97 GPR132 (0.77) GPR132PTPN1PPARGGPR34ITGB3
SCHEMBL1122833 0.96 GPR132 (0.72) GPR132PTPN1PPARGGPR34ITGB3
SCHEMBL5927205 0.96 GPR132 (0.72) GPR132PTPN1PPARGGPR34ITGB3
SCHEMBL1123243 0.96 GPR132 (0.72) GPR132PTPN1PPARGGPR34ITGB3
SCHEMBL1123309 0.95 GPR132 (0.71) GPR132PTPN1PPARGGPR34ITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1835914-A New benzamides as PPAR[upsilon] modulators S A L V A T LAB SA (ES) 2006-09-20 CN claimed
CN-1835914-A New benzamides as PPAR[upsilon] modulators S A L V A T LAB SA (ES) 2006-09-20 CN disclosed