Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 20/20 | 0.64 |
| ▸ | ESRRB | O95718 | 2/20 | 0.47 |
| ▸ | ESRRA | P11474 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3925753 | 0.91 | ESR1 (0.67) | ESR1ESR2ESRRBESRRA | |
| SCHEMBL27659342 | 0.87 | ESR1 (0.54) | ESR1ESR2ESRRBESRRA | |
| SCHEMBL27659447 | 0.83 | ESR1 (0.86) | ESR1ESR2ESRRBESRRA | |
| SCHEMBL3927684 | 0.78 | ESR1 (1.00) | ESR1ESR2ESRRBESRRA | |
| SCHEMBL27638480 | 0.77 | ESR1 (0.59) | ESR1ESR2ESRRBESRRA | |
| SCHEMBL3922723 | 0.72 | ESR1 (0.63) | ESR1ESR2ESRRBESRRA | |
| SCHEMBL13607751 | 0.72 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL27659448 | 0.71 | ESR1 (0.72) | ESR1ESR2ESRRBESRRA | |
| SCHEMBL3929956 | 0.70 | ESR1 (1.00) | ESR1ESR2ESRRBESRRA | |
| SCHEMBL3928048 | 0.70 | ESR1 (0.65) | ESR1ESR2ESRRBESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1823046-A | Phenyl quinolines and their use as estrogen receptor modulators | WYETH CORP (US) | 2006-08-23 | — | — | CN | claimed |
| CN-1823046-A | Phenyl quinolines and their use as estrogen receptor modulators | WYETH CORP (US) | 2006-08-23 | — | — | CN | disclosed |