SCHEMBL27659751

SCHEMBL27659751

CN(CC1CCN(OC(=O)C(C)(C)C)CC1)c1ncnc2c1cnn2-c1ccc(S(C)(=O)=O)cc1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27638978 0.91 GPR119 (0.79) GPR119
SCHEMBL27659871 0.90 GPR119 (0.69) GPR119
SCHEMBL27659921 0.89 GPR119 (0.63) GPR119
SCHEMBL389100 0.88 GPR119 (1.00) GPR119
SCHEMBL27639082 0.88 GPR119 (0.60) GPR119
SCHEMBL27939115 0.84 GPR119 (0.57) GPR119
SCHEMBL14548386 0.83 GPR119 (0.79) GPR119
SCHEMBL27638961 0.80 GPR119 (0.60) GPR119
Tert-Butyl Formate SCHEMBL27659753 0.80 GPR119 (0.68) GPR119
SCHEMBL28757816 0.80 GPR119 (0.75) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1829718-A Fused aryl and heteroaryl derivatives as modulators of metabolism and the prevention and treatment of disorders related thereto ARENA PHARM INC (US) 2006-09-06 CN claimed
CN-103611161-A Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood GLP-1 level ARENA PHARM INC 2014-03-05 CN disclosed
CN-102417508-A Fused aryl and heteroaryl derivatives as modulators of metabolism and the prevention and treatment of disorders related thereto ARENA PHARM INC 2012-04-18 CN disclosed
CN-1829718-A Fused aryl and heteroaryl derivatives as modulators of metabolism and the prevention and treatment of disorders related thereto ARENA PHARM INC (US) 2006-09-06 CN disclosed