Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL27981758 | 0.97 | TSHR (0.50) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL11258995 | 0.95 | TSHR (0.47) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL14645659 | 0.94 | TSHR (0.60) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL3153156 | 0.88 | TSHR (0.60) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL1629138 | 0.86 | TSHR (0.39) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL3153149 | 0.82 | TSHR (0.53) | TSHRNAPRTTDP1 | |
| Pyrimidine SCHEMBL27965432 | 0.82 | TSHR (0.30) | TSHRNAPRTTDP1 | |
| Pyrazine SCHEMBL17362417 | 0.81 | — | — | |
| Cyclohexane SCHEMBL1898523 | 0.77 | TSHR (0.75) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL6114733 | 0.77 | TSHR (0.75) | TSHRNAPRTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924313-A | Tetrahydrothienopyridine derivative and preparation method and application thereof | 仁合益康集团有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-116102524-A | Asymmetric synthesis method of beta-amino alcohol compound | 华东理工大学 | 2023-05-12 | — | — | CN | claimed |
| CN-104045652-A | Preparation method of clopidogrel intermediate compound | JIANFENG SHEN | 2014-09-17 | — | — | CN | claimed |
| CN-101948479-B | Prasugrel intermediate and preparation method thereof | HENGDIAN GROUP JIAYUAN CHEMICAL INDUSTRY CO LTD | 2013-01-30 | — | — | CN | claimed |
| CN-101948479-A | Prasugrel intermediate and preparation method thereof | HEIDIAN GROUP JIAYUAN CHEMICALS CO LTD | 2011-01-19 | — | — | CN | claimed |
| CN-117924313-A | Tetrahydrothienopyridine derivative and preparation method and application thereof | 仁合益康集团有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117924313-A | Tetrahydrothienopyridine derivative and preparation method and application thereof | 仁合益康集团有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-116102524-A | Asymmetric synthesis method of beta-amino alcohol compound | 华东理工大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-111943958-B | Crystal form B of tetrahydrothiophene pyridine compound as well as preparation method, composition and application thereof | 成都施贝康生物医药科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-111943958-B | Crystal form B of tetrahydrothiophene pyridine compound as well as preparation method, composition and application thereof | 成都施贝康生物医药科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-111943958-B | Crystal form B of tetrahydrothiophene pyridine compound as well as preparation method, composition and application thereof | 成都施贝康生物医药科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-108069855-B | Method for recycling S-o-chloromandelic acid | 鲁南制药集团股份有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-104045652-A | Preparation method of clopidogrel intermediate compound | JIANFENG SHEN | 2014-09-17 | — | — | CN | disclosed |
| CN-103772270-A | Metabolin marker of 2-hydroxyl radical tetrahydro-thiophene pyridine derivative with optical activity as well as preparation and application thereof | JIANGSU VCARE PHARMATECH CO LTD | 2014-05-07 | — | — | CN | disclosed |
| CN-103772270-A | Metabolin marker of 2-hydroxyl radical tetrahydro-thiophene pyridine derivative with optical activity as well as preparation and application thereof | JIANGSU VCARE PHARMATECH CO LTD | 2014-05-07 | — | — | CN | disclosed |
| CN-101948479-B | Prasugrel intermediate and preparation method thereof | HENGDIAN GROUP JIAYUAN CHEMICAL INDUSTRY CO LTD | 2013-01-30 | — | — | CN | disclosed |
| CN-101948479-A | Prasugrel intermediate and preparation method thereof | HEIDIAN GROUP JIAYUAN CHEMICALS CO LTD | 2011-01-19 | — | — | CN | disclosed |
| CN-100503614-C | Thiofurantetrahydropyridine derivative optical isomer racemization method | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2009-06-24 | — | — | CN | disclosed |
| CN-1951941-A | Thiofurantetrahydropyridine derivative optical isomer racemization method | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2007-04-25 | — | — | CN | disclosed |