Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27932682 | 0.84 | GRM1 (0.52) | ALDH1A1KDM4ENPSR1HSD17B10ADRB2 | |
| SCHEMBL10858817 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4ENPSR1HSD17B10ADRB2 | |
| SCHEMBL10858811 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4ENPSR1HSD17B10ADRB2 | |
| SCHEMBL3866767 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4ENPSR1HSD17B10ADRB2 | |
| SCHEMBL4546626 | 0.77 | ALDH1A1 (0.74) | ALDH1A1KDM4EHSD17B10ADRB2TSHR | |
| SCHEMBL7068390 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4ENPSR1HSD17B10ADRB2 | |
| SCHEMBL7068386 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4ENPSR1HSD17B10ADRB2 | |
| SCHEMBL2252745 | 0.76 | ALDH1A1 (0.58) | ALDH1A1KDM4ENPSR1HSD17B10ADRB2 | |
| SCHEMBL2249019 | 0.76 | ALDH1A1 (0.58) | ALDH1A1KDM4ENPSR1HSD17B10ADRB2 | |
| SCHEMBL10859134 | 0.76 | KDM4E (0.73) | ALDH1A1KDM4ENPSR1HSD17B10ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989106-B | N-hydroxyamide derivatives and their use | MERCK SERONO SA | 2013-12-04 | — | — | CN | claimed |
| CN-1989106-A | N-hydroxyamide derivatives and their use | APPLIED RESEARCH SYSTEMS (AN) | 2007-06-27 | — | — | CN | claimed |
| CN-1989106-B | N-hydroxyamide derivatives and their use | MERCK SERONO SA | 2013-12-04 | — | — | CN | disclosed |
| CN-1989106-A | N-hydroxyamide derivatives and their use | APPLIED RESEARCH SYSTEMS (AN) | 2007-06-27 | — | — | CN | disclosed |