Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659876 | 0.80 | TDP1 (0.39) | TDP1 | |
| SCHEMBL28794684 | 0.71 | TDP1 (0.31) | TDP1 | |
| SCHEMBL19478704 | 0.70 | CYP2B6 (0.41) | CYP2B6 | |
| Cyclooctane SCHEMBL21693719 | 0.69 | TDP1 (0.81) | TDP1 | |
| SCHEMBL19520207 | 0.69 | CYP2B6 (0.35) | CYP2B6 | |
| SCHEMBL13860177 | 0.69 | CYP2B6 (0.35) | CYP2B6 | |
| SCHEMBL30785507 | 0.68 | TDP1 (0.36) | TDP1 | |
| SCHEMBL23598527 | 0.67 | CYP2B6 (0.38) | CYP2B6 | |
| Tert-Butyl Formate SCHEMBL28876682 | 0.66 | TDP1 (0.48) | TDP1 | |
| SCHEMBL9707183 | 0.65 | CYP2B6 (0.32) | CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101896481-B | Pyrimidyl indoline compound | DAIICHI SANKYO CO LTD | 2014-04-30 | — | — | CN | claimed |
| CN-102007126-A | Compounds and compositions as modulators of gpr119 activity | IRM LLC | 2011-04-06 | — | — | CN | claimed |
| CN-101896481-A | Pyrimidyl indoline compound | DAIICHI SANKYO CO LTD | 2010-11-24 | — | — | CN | claimed |
| CN-109923108-A | Pyridyl-substituted indole compounds | 百时美施贵宝公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-109715617-A | Dimethoxyphenyl-substituted indole compounds as inhibitors of TLR7, TLR8 or TLR9 | 百时美施贵宝公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-108884043-A | Substituted piperidine compounds and uses thereof | 武田药品工业株式会社 | 2018-11-23 | — | — | CN | disclosed |
| CN-106470985-A | Indane and indoline derivatives as soluble guanylate cyclase activators and uses thereof | 诺华股份有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-102459222-B | L- (piperidin-4-yl) -pyrazole derivatives as GPR119 modulators | PFIZER | 2014-06-04 | — | — | CN | disclosed |
| CN-101896481-B | Pyrimidyl indoline compound | DAIICHI SANKYO CO LTD | 2014-04-30 | — | — | CN | disclosed |
| CN-103550218-A | Pyridone gpr119 g protein-coupled receptor agonists | BRISTOL MYERS SQUIBB CO | 2014-02-05 | — | — | CN | disclosed |
| CN-101801956-B | Methods for modulating GPR 119G protein-coupled receptors and selected compounds | BRISTOL MYERS SQUIBB CO | 2013-11-20 | — | — | CN | disclosed |
| CN-101484441-A | Modulators of metabolism and the treatment of disorders related thereto | ARENA PHARM INC (US) | 2009-07-15 | — | — | CN | disclosed |
| CN-101484440-A | Modulators of metabolism and the treatment of disorders related thereto | ARENA PHARM INC (US) | 2009-07-15 | — | — | CN | disclosed |
| CN-100509798-C | Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prevention and treatment of disorders related thereto | ARENA PHARM INC (US) | 2009-07-08 | — | — | CN | disclosed |
| CN-101263135-A | Modulators of metabolism and treatment of metabolic-related disorders | ARENA PHARM INC (US) | 2008-09-10 | — | — | CN | disclosed |
| CN-101146806-A | Pyrazole derivatives for the inhibition of CDK and GSK | ASTEX THERAPEUTICS LTD (GB) | 2008-03-19 | — | — | CN | disclosed |
| CN-101142216-A | Process for preparing pyrazolo [3, 4-D ] pyrimidine ethers | ARENA PHARM INC (US) | 2008-03-12 | — | — | CN | disclosed |
| CN-101115740-A | Treatment of substituted pyridyl and pyrimidinyl derivatives and related diseases as metabolic modulators | ARENA PHARM INC (US) | 2008-01-30 | — | — | CN | disclosed |
| CN-101115739-A | Process for preparing 4- (phenoxy-5-methyl-pyrimidin-4-yloxy) piperidine-1-carboxylic acid derivatives and related compounds | ARENA PHARM INC (US) | 2008-01-30 | — | — | CN | disclosed |
| CN-1823056-A | Trisubstituted aryl and heteroaryl derivatives as modulatorsof metabolism and the prophylaxis and treatment of disorders related thereto | ARENA PHARM INC (US) | 2006-08-23 | — | — | CN | disclosed |