SCHEMBL28659876

SCHEMBL28659876

CN1CCN(C(C)(C)OC=O)CC1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27814591 0.80 TDP1 (0.40) TDP1
SCHEMBL27660840 0.80 TDP1 (0.40) TDP1
SCHEMBL27759734 0.75 TDP1 (0.36) TDP1
SCHEMBL27659800 0.74 TDP1 (0.34) TDP1
Tert-Butyl Formate SCHEMBL28267336 0.71 TDP1 (0.59) TDP1
SCHEMBL27909015 0.71 TDP1 (0.32) TDP1
SCHEMBL15515140 0.70 TDP1 (0.32) TDP1
SCHEMBL28794684 0.70 TDP1 (0.31) TDP1
SCHEMBL27908929 0.70 TDP1 (0.31) TDP1
Tert-Butyl Formate SCHEMBL27767519 0.70 TDP1 (0.56) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113552241-A Method for determining residual content of 4-methylpiperazine-1-formate genotoxic impurities in zopiclone 江苏天士力帝益药业有限公司 2021-10-26 CN claimed
CN-114763342-A Synthesis method of high-purity 4-methylpiperazine-1-formic ether 江苏天士力帝益药业有限公司 2022-07-19 CN disclosed
CN-113552241-A Method for determining residual content of 4-methylpiperazine-1-formate genotoxic impurities in zopiclone 江苏天士力帝益药业有限公司 2021-10-26 CN disclosed
CN-113552241-A Method for determining residual content of 4-methylpiperazine-1-formate genotoxic impurities in zopiclone 江苏天士力帝益药业有限公司 2021-10-26 CN disclosed