Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27681019 | 0.82 | NR4A3 (0.54) | NR4A3MAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL27660961 | 0.80 | NR4A3 (0.58) | NR4A3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL12340468 | 0.77 | NR4A3 (0.56) | NR4A3MAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL4041244 | 0.76 | NR4A3 (0.59) | NR4A3MAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL27681018 | 0.74 | NR4A3 (0.61) | NR4A3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL4037627 | 0.73 | NR4A3 (0.59) | NR4A3MAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL12338161 | 0.72 | NR4A3 (0.66) | NR4A3MAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL27596217 | 0.69 | GABRA1 (0.38) | MAPTNPSR1NFKB1TSHRL3MBTL1 | |
| SCHEMBL18265951 | 0.69 | NR4A3 (0.61) | NR4A3MAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL4036784 | 0.69 | NR4A3 (0.74) | NR4A3MAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930144-A | 3-'4-heterocyclyl -1,2,3,-triazol-1-yl!-n-aryl-benzamides as inhibitors of the cytokines production for the treatment of chronic inflammatory diseases | BOEHRINGER INGELHEIM PHARMA (US) | 2007-03-14 | — | — | CN | disclosed |