Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | IL2 | P60568 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27682952 | 0.81 | DAO (0.47) | DAODDO | |
| SCHEMBL2075092 | 0.79 | HTR2A (0.51) | HRH1HTR1B | |
| SCHEMBL27663367 | 0.78 | LOXL2 (0.44) | DAO | |
| SCHEMBL16380961 | 0.74 | DAO (0.49) | DAODDOCA12CA9HRH4 | |
| SCHEMBL20826030 | 0.73 | DAO (0.40) | DAODDOCA12CA9HRH4 | |
| SCHEMBL20826032 | 0.73 | DAO (0.40) | DAODDOCA12CA9HRH4 | |
| SCHEMBL28776189 | 0.69 | SLC6A2 (0.38) | HRH1 | |
| SCHEMBL27663475 | 0.69 | CNR1 (0.39) | DAOCNR1 | |
| SCHEMBL2074077 | 0.68 | HTR2A (0.51) | DAODDOHRH1HTR1B | |
| SCHEMBL3293424 | 0.68 | DAO (0.53) | DAODDOCA12CA9HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1993321-A | 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitors | HOFFMANN LA ROCHE (CH) | 2007-07-04 | — | — | CN | disclosed |