Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.77 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.69 |
| ▸ | ACR | P10323 | 1/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.69 |
| ▸ | CHUK | O15111 | 1/20 | 0.60 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.60 |
| ▸ | PRKCG | P05129 | 1/20 | 0.60 |
| ▸ | CDK1 | P06493 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.60 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | AKT1 | P31749 | 1/20 | 0.60 |
| ▸ | AKT2 | P31751 | 1/20 | 0.60 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.60 |
| ▸ | BLK | P51451 | 1/20 | 0.60 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.60 |
| ▸ | JAK3 | P52333 | 1/20 | 0.60 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27663831 | 0.89 | FURIN (0.76) | FURINPRSS1ACRADRA2ACHUK | |
| SCHEMBL4099965 | 0.82 | ADRA2A (1.00) | FURINPRSS1ACRADRA2AHTR3E | |
| SCHEMBL27663838 | 0.81 | FURIN (0.73) | FURINPRSS1ACRADRA2AHTR3E | |
| SCHEMBL3727389 | 0.79 | NR5A1 (0.75) | GAARAB9ANPC1LMNATP53 | |
| 1-Butyloxy-4-Pentoxybenzene SCHEMBL12827001 | 0.79 | NR5A1 (0.75) | GAARAB9ANPC1LMNATP53 | |
| SCHEMBL4765711 | 0.79 | FURIN (0.65) | FURINPRSS1ACRADRA2AMAPT | |
| SCHEMBL4397713 | 0.78 | NR5A1 (0.63) | GAARAB9ANPC1LMNATP53 | |
| SCHEMBL5486908 | 0.78 | NR5A1 (0.63) | GAARAB9ANPC1LMNATP53 | |
| SCHEMBL11037329 | 0.78 | NR5A1 (0.63) | GAARAB9ANPC1LMNATP53 | |
| SCHEMBL5349508 | 0.78 | NR5A1 (0.63) | GAARAB9ANPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989120-A | Guanidine derivatives and their therapeutic use | MERCK PATENT GMBH (DE) | 2007-06-27 | — | — | CN | claimed |
| CN-1989120-A | Guanidine derivatives and their therapeutic use | MERCK PATENT GMBH (DE) | 2007-06-27 | — | — | CN | disclosed |