Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801030 | 0.84 | MAOB (0.60) | ALDH1A1MAPTKMT2ANOS1HMOX2 | |
| SCHEMBL98467 | 0.83 | KDM4E (0.54) | ALDH1A1MAPTKMT2ANOS1HMOX2 | |
| SCHEMBL7162438 | 0.82 | MAOB (0.62) | ALDH1A1MAPTKMT2ANOS1HMOX2 | |
| SCHEMBL13883739 | 0.80 | MAOB (0.64) | ALDH1A1MAPTKMT2ANOS1HMOX2 | |
| SCHEMBL23071123 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2ANOS1HMOX2 | |
| SCHEMBL30379123 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2ANOS1HMOX2 | |
| SCHEMBL30594499 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2ANOS1HMOX2 | |
| SCHEMBL5251518 | 0.78 | KDM4E (0.52) | ALDH1A1MAPTKMT2ANOS1HMOX2 | |
| SCHEMBL12370654 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2ANOS1HMOX2 | |
| SCHEMBL21176752 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2ANOS1HMOX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101024671-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2010-08-18 | — | — | CN | disclosed |
| CN-1974596-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2010-07-28 | — | — | CN | disclosed |
| CN-101024671-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2007-08-29 | — | — | CN | disclosed |
| CN-1974596-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2007-06-06 | — | — | CN | disclosed |