Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801003 | 0.64 | PDE4A (0.30) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31419892 | 0.57 | SMN1; SMN2 (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2117765 | 0.57 | SMN1; SMN2 (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6916146 | 0.55 | — | — | |
| SCHEMBL1350019 | 0.55 | — | — | |
| SCHEMBL83401 | 0.55 | — | — | |
| SCHEMBL12559248 | 0.55 | — | — | |
| SCHEMBL41301 | 0.55 | — | — | |
| SCHEMBL2128819 | 0.55 | — | — | |
| Pyrimidine SCHEMBL28167288 | 0.54 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1993362-B | Fused Heterocyclic Compounds | TAKEDA PHARMACEUTICAL | 2010-12-15 | — | — | CN | disclosed |
| CN-1993362-A | Fused Heterocyclic Compounds | TAKEDA PHARMACEUTICAL (JP) | 2007-07-04 | — | — | CN | disclosed |