Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27684802 | 0.86 | ANPEP (0.60) | ANPEPRAB9AALDH1A1SMN1; SMN2NR3C2 | |
| SCHEMBL28765381 | 0.85 | MEN1 (0.75) | ANPEPKMT2AMEN1NPC1RAB9A | |
| SCHEMBL10690937 | 0.81 | CASR (0.62) | CASRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL6258166 | 0.80 | CASR (0.61) | CASRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL27684533 | 0.80 | MEN1 (0.70) | ANPEPKMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27489902 | 0.79 | CASR (0.60) | CASRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL17152274 | 0.79 | ANPEP (0.61) | CASRANPEPKMT2AMEN1NPC1 | |
| SCHEMBL8122142 | 0.79 | ALDH1A1 (0.60) | CASRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL12757447 | 0.77 | ALDH1A1 (0.62) | ANPEPKMT2AMEN1NPC1RAB9A | |
| SCHEMBL27665008 | 0.77 | MEN1 (0.55) | KMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1910144-B | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD | 2010-06-09 | — | — | CN | claimed |
| CN-1910144-A | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD (US) | 2007-02-07 | — | — | CN | claimed |
| CN-1910144-B | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD | 2010-06-09 | — | — | CN | disclosed |
| CN-1910144-A | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD (US) | 2007-02-07 | — | — | CN | disclosed |