Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388684 | 0.75 | NAAA (0.39) | NAAASLC18A3ALDH1A1CYP2C19LMNA | |
| SCHEMBL8402329 | 0.73 | SLC6A2 (0.31) | — | |
| SCHEMBL27929750 | 0.73 | NAAA (0.39) | NAAASLC18A3ALDH1A1CYP19A1 | |
| SCHEMBL888425 | 0.71 | NAAA (0.42) | NAAASMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL9733085 | 0.69 | — | — | |
| SCHEMBL3189181 | 0.69 | NAAA (0.52) | NAAASLC18A3ALDH1A1KMT2ACHRM1 | |
| SCHEMBL1695592 | 0.69 | NAAA (0.72) | NAAASLC18A3ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL3189185 | 0.69 | NAAA (0.52) | NAAASLC18A3ALDH1A1KMT2ACHRM1 | |
| SCHEMBL9968594 | 0.69 | KMT2A (0.38) | ALDH1A1SMN1; SMN2KMT2APOLBATM | |
| SCHEMBL8690677 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408321-B | Indoles and azole derivatives, their preparation method and the pharmaceutical composition containing them | 法国施维雅药厂 | 2019-03-08 | — | — | CN | disclosed |
| CN-105408321-A | Novel derivatives of indole and pyrrole, method for the production thereof and pharmaceutical compositions containing same | SERVIER LAB | 2016-03-16 | — | — | CN | disclosed |
| CN-1950337-A | (4, 5,6, 7-tetrahydro-1-H-indol-7-yl) acetic acid derivatives for the treatment of Alzheimer's disease | MERCK SHARP & DOHME (GB) | 2007-04-18 | — | — | CN | disclosed |