Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | CPN1 | P15169 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711465 | 1.00 | HRH3 (0.46) | HRH3KMT2ANAAAHRH4CPN1 | |
| SCHEMBL27898974 | 0.94 | HRH3 (0.47) | HRH3KMT2ANAAAHRH4CPN1 | |
| SCHEMBL11170648 | 0.87 | HRH3 (0.51) | HRH3KMT2ANAAAHRH4CPN1 | |
| SCHEMBL6617754 | 0.85 | — | — | |
| SCHEMBL7704486 | 0.85 | HRH3 (0.53) | HRH3KMT2ANAAAHRH4CPN1 | |
| Bromide SCHEMBL11208446 | 0.83 | HRH3 (0.44) | HRH3KMT2ANAAAHRH4CPN1 | |
| SCHEMBL11980479 | 0.81 | — | — | |
| SCHEMBL5663061 | 0.80 | HRH3 (0.46) | HRH3KMT2ANAAAHRH4CPN1 | |
| SCHEMBL902268 | 0.80 | CYP1A2 (0.48) | HRH3KMT2ANAAAHRH4CPN1 | |
| SCHEMBL9036494 | 0.80 | HRH3 (0.46) | HRH3KMT2ANAAAHRH4CPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228127-B | Piperidine derivatives | BANYU PHARMA CO LTD | 2012-05-16 | — | — | CN | disclosed |
| CN-1960977-B | Quinazoline derivative | BANYU PHARMA CO LTD | 2010-07-21 | — | — | CN | disclosed |
| CN-101228127-A | Novel Piperidine Derivatives | BANYU PHARMA CO LTD (JP) | 2008-07-23 | — | — | CN | disclosed |
| CN-1960977-A | Quinazoline derivative | BANYU PHARMA CO LTD (JP) | 2007-05-09 | — | — | CN | disclosed |