Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666033 | 0.85 | CHRM4 (0.39) | TP53MEN1KMT2ASCN10ASLC6A2 | |
| SCHEMBL28761513 | 0.81 | CHRM4 (0.49) | TP53MEN1KMT2ASCN10ASLC6A2 | |
| SCHEMBL2096022 | 0.76 | ADRB2 (0.49) | TP53MEN1KMT2ASCN10ASLC6A2 | |
| SCHEMBL2096017 | 0.76 | ADRB2 (0.49) | TP53MEN1KMT2ASCN10ASLC6A2 | |
| SCHEMBL27644493 | 0.74 | TP53 (0.46) | TP53MEN1KMT2ASCN10ASLC6A2 | |
| SCHEMBL27665945 | 0.73 | EPHX2 (0.38) | EPHX2CHRM4 | |
| SCHEMBL20858622 | 0.71 | SLC6A2 (0.69) | TP53MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL2090360 | 0.71 | SCN10A (0.41) | TP53MEN1KMT2ASCN10ASLC6A2 | |
| SCHEMBL2090364 | 0.71 | SCN10A (0.41) | TP53MEN1KMT2ASCN10ASLC6A2 | |
| SCHEMBL5544454 | 0.71 | TP53 (0.59) | TP53MEN1KMT2ASCN10ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |