Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097574 | 0.90 | CYP2E1 (0.30) | — | |
| SCHEMBL9111503 | 0.84 | MEN1 (0.32) | MEN1USP2MAPTALOX15KMT2A | |
| SCHEMBL2091183 | 0.82 | MEN1 (0.34) | MEN1USP2MAPTALOX15KMT2A | |
| SCHEMBL2095499 | 0.75 | MEN1 (0.42) | MEN1USP2MAPTALOX15KMT2A | |
| SCHEMBL8051996 | 0.75 | MEN1 (0.36) | MEN1USP2MAPTALOX15KMT2A | |
| SCHEMBL27329701 | 0.74 | MEN1 (0.38) | MEN1USP2MAPTALOX15KMT2A | |
| SCHEMBL2092294 | 0.72 | ESR1 (0.31) | — | |
| SCHEMBL6598549 | 0.68 | MEN1 (0.39) | MEN1USP2MAPTALOX15KMT2A | |
| SCHEMBL28141334 | 0.68 | USP2 (0.39) | MEN1USP2MAPTALOX15KMT2A | |
| SCHEMBL28104229 | 0.68 | MEN1 (0.36) | MEN1USP2MAPTALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |