Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412578 | 0.79 | LTA4H (0.46) | KDM4EHSD17B10TSHRLMNATDP1 | |
| SCHEMBL4804791 | 0.77 | TDP1 (0.47) | KDM4EHSD17B10TSHRLMNATDP1 | |
| SCHEMBL2648411 | 0.76 | CA12 (0.53) | KDM4EHSD17B10TSHRLMNACA1 | |
| SCHEMBL30474373 | 0.74 | CA12 (0.52) | KDM4EHSD17B10TSHRLMNATDP1 | |
| SCHEMBL12316454 | 0.74 | CA12 (0.52) | KDM4EHSD17B10TSHRLMNATDP1 | |
| SCHEMBL4456195 | 0.74 | CA12 (0.62) | KDM4EHSD17B10TSHRLMNATDP1 | |
| SCHEMBL8844738 | 0.74 | CA12 (0.57) | KDM4EHSD17B10TSHRLMNATDP1 | |
| SCHEMBL4955520 | 0.74 | TDP1 (0.54) | KDM4EHSD17B10TSHRLMNATDP1 | |
| Dimethyl Phthalate SCHEMBL28487305 | 0.73 | TDP1 (0.65) | KDM4EHSD17B10TSHRLMNATDP1 | |
| SCHEMBL31522017 | 0.73 | TDP1 (0.52) | KDM4EHSD17B10TSHRLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101180097-A | Novel phosphinic acid-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2008-05-14 | — | — | CN | disclosed |
| CN-1882327-A | Novel phosphorus-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2006-12-20 | — | — | CN | disclosed |