Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.47 |
| ▸ | LCK | P06239 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1256069 | 0.88 | ADORA2A (0.52) | ADORA2AADORA1LCKL3MBTL1HSP90AA1 | |
| SCHEMBL27647745 | 0.87 | LCK (0.48) | ADORA2AADORA1LCKL3MBTL1HSP90AA1 | |
| SCHEMBL27647708 | 0.84 | L3MBTL1 (0.48) | ADORA2AADORA1LCKL3MBTL1HSP90AA1 | |
| SCHEMBL1256328 | 0.84 | ADORA2A (0.55) | ADORA2AADORA1L3MBTL1HSP90AA1KDM4E | |
| SCHEMBL27668139 | 0.84 | ADORA2A (0.69) | ADORA2AADORA1ALDH1A1LMNAMAPT | |
| SCHEMBL27647702 | 0.84 | LCK (0.46) | ADORA2AADORA1LCKL3MBTL1HSP90AA1 | |
| SCHEMBL27668182 | 0.83 | KDM4E (0.51) | ADORA2AADORA1LCKL3MBTL1HSP90AA1 | |
| SCHEMBL1254127 | 0.83 | MEN1 (0.57) | ADORA2AADORA1LCKL3MBTL1KDM4E | |
| SCHEMBL1256213 | 0.82 | KDM4E (0.45) | ADORA2AADORA1LCKL3MBTL1HSP90AA1 | |
| SCHEMBL27668150 | 0.82 | ADORA2A (0.57) | ADORA2AADORA1LCKALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1902196-B | Thiazole derivatives | KYOWA HAKKO KOGYO KK | 2010-12-29 | — | — | CN | disclosed |
| CN-1902196-A | Thiazole derivatives | KYOWA HAKKO KOGYO KK (JP) | 2007-01-24 | — | — | CN | disclosed |