Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28133365 | 0.94 | DGKA (0.53) | DGKALMNACNR2PAMSPHK2 | |
| SCHEMBL1180260 | 0.94 | DGKA (0.53) | DGKALMNACNR2PAMSPHK2 | |
| SCHEMBL1179755 | 0.94 | DGKA (0.53) | DGKALMNACNR2PAMSPHK2 | |
| SCHEMBL9273172 | 0.94 | DGKA (0.53) | DGKALMNACNR2PAMSPHK2 | |
| SCHEMBL825469 | 0.94 | DGKA (0.53) | DGKALMNACNR2PAMSPHK2 | |
| SCHEMBL27838257 | 0.93 | DGKA (0.52) | DGKALMNACNR2PAMSPHK2 | |
| SCHEMBL11254862 | 0.93 | DGKA (0.50) | DGKALMNACNR2PAMSPHK2 | |
| SCHEMBL2172442 | 0.87 | CES1 (0.42) | DGKALMNACNR2PAMSPHK2 | |
| SCHEMBL9276219 | 0.85 | CNR2 (0.64) | LMNACNR2MAPTMEN1FAAH | |
| SCHEMBL27500866 | 0.84 | TSHR (0.40) | DGKALMNACNR2PAMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1870955-A | Kavalactone compositions and methods of use | KAVA PHARMACEUTICALS INC (US) | 2006-11-29 | — | — | CN | disclosed |