Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3509625 | 0.94 | STAT3 (0.35) | TP53MAPTSTAT3STAT1 | |
| SCHEMBL18222562 | 0.85 | — | — | |
| Quinoline SCHEMBL28774730 | 0.81 | ALDH1A1 (0.38) | TP53MAPTSTAT3STAT1 | |
| SCHEMBL31344426 | 0.78 | STAT3 (0.37) | MAPTSTAT3STAT1 | |
| SCHEMBL144249 | 0.78 | STAT3 (0.37) | MAPTSTAT3STAT1 | |
| SCHEMBL27857593 | 0.78 | STAT3 (0.33) | STAT3STAT1 | |
| Methoxymethane SCHEMBL27581743 | 0.77 | STAT3 (0.38) | STAT3STAT1 | |
| Methoxymethane SCHEMBL28698428 | 0.77 | STAT3 (0.38) | STAT3STAT1 | |
| SCHEMBL29470202 | 0.77 | STAT3 (0.36) | MAPTSTAT3STAT1 | |
| SCHEMBL29790221 | 0.77 | STAT3 (0.36) | MAPTSTAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101913973-A | Preparation and use of alkylating agents | QUEENS MEDICAL CT | 2010-12-15 | — | — | CN | claimed |
| CN-1886362-A | Preparation and use of alkylating agents | QUEENS MEDICAL CT (US) | 2006-12-27 | — | — | CN | claimed |
| CN-101913973-B | Preparation and use of alkylating agents | QUEENS MEDICAL CT | 2013-11-20 | — | — | CN | disclosed |
| CN-101913973-A | Preparation and use of alkylating agents | QUEENS MEDICAL CT | 2010-12-15 | — | — | CN | disclosed |