Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784603 | 0.84 | IKBKB (0.59) | IKBKBCHUK | |
| SCHEMBL2767015 | 0.84 | CHUK (0.45) | IKBKBCHUK | |
| SCHEMBL3551413 | 0.79 | IKBKB (0.53) | IKBKBCHUK | |
| SCHEMBL3039776 | 0.78 | IKBKB (0.47) | IKBKBCHUK | |
| SCHEMBL2766887 | 0.74 | IKBKB (0.55) | IKBKBCHUK | |
| SCHEMBL2769650 | 0.72 | IKBKB (0.68) | IKBKBCHUK | |
| SCHEMBL2768475 | 0.72 | IKBKB (0.65) | IKBKBCHUK | |
| SCHEMBL2767732 | 0.72 | IKBKB (0.65) | IKBKBCHUK | |
| SCHEMBL3041538 | 0.72 | IKBKB (0.75) | IKBKBCHUK | |
| SCHEMBL2786241 | 0.70 | IKBKB (0.68) | IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888584-B1 | 1, 6 -DIHYDRO- 1,3, 5, 6-TETRAAZA-AS-INDACENE BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AS INHIBITORS OF IKK ENZYME ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2010-04-21 | — | — | EP | disclosed |