Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2767014 | 0.84 | IKBKB (0.49) | CHUKIKBKB | |
| SCHEMBL2784605 | 0.83 | IKBKB (0.54) | CHUKIKBKB | |
| SCHEMBL12341877 | 0.82 | IKBKB (0.62) | CHUKIKBKB | |
| SCHEMBL12341966 | 0.82 | CHUK (0.53) | CHUKIKBKB | |
| SCHEMBL12341878 | 0.80 | IKBKB (0.68) | CHUKIKBKB | |
| SCHEMBL12341887 | 0.80 | CHUK (0.59) | CHUKIKBKB | |
| SCHEMBL12342080 | 0.79 | CHUK (0.46) | CHUKIKBKB | |
| SCHEMBL2767726 | 0.79 | CHUK (0.46) | CHUKIKBKB | |
| SCHEMBL2767370 | 0.79 | IKBKB (0.57) | CHUKIKBKB | |
| SCHEMBL2768396 | 0.79 | CHUK (0.57) | CHUKIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888584-B1 | 1, 6 -DIHYDRO- 1,3, 5, 6-TETRAAZA-AS-INDACENE BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AS INHIBITORS OF IKK ENZYME ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2010-04-21 | — | — | EP | disclosed |