SCHEMBL27670185

SCHEMBL27670185

CCCc1ccc(C(=O)c2ccccc2)c(N)c1CCC

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
ADORA2A P29274 1/20 0.41
PTGS1 P23219 2/20 0.40
PTGS2 P35354 2/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
MAPK14 Q16539 1/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GLA P06280 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ABCB11 O95342 1/20 0.39
ADORA1 P30542 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL743150 0.83 MAPT (0.47) MAPTGAAPTGS1PTGS2MAPK14
SCHEMBL27789467 0.83 GABRP (0.43) PPARA
SCHEMBL9626492 0.80 AKR1C3 (0.46) MAPTGAAPPARGPPARAALDH1A1
SCHEMBL30549386 0.80 MAPT (0.50) MAPTGAAPTGS1PTGS2MAPK14
SCHEMBL27689289 0.79 MAPT (0.46) MAPTGAAPTGS2MAPK14LMNA
SCHEMBL11591106 0.78 PBRM1 (0.47) MAPTGAAPTGS1PTGS2PPARG
SCHEMBL4091414 0.77 PTGS1 (0.49) MAPTGAAPTGS1PTGS2LMNA
SCHEMBL27350244 0.77 CNR2 (0.58) MAPTPPARGPPARALMNAPOLB
SCHEMBL2855431 0.77 PPARG (0.46) MAPTGAAPPARGPPARALMNA
SCHEMBL7252078 0.76 AKR1C3 (0.52) MAPTGAAPPARGPPARAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1987649-A Photo setting composition and color filter FUJI FILM ELECTRONIC MATERIAL (JP) 2007-06-27 CN disclosed