Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TOP2A | P11388 | 5/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | KHK | P50053 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27678002 | 0.85 | MEN1 (0.53) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27689345 | 0.84 | KDM4E (0.51) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11711995 | 0.82 | KDM4E (0.67) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL5546381 | 0.82 | KDM4E (0.67) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11713970 | 0.82 | LMNA (0.50) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL5429854 | 0.81 | TOP1 (0.43) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL11712537 | 0.81 | LMNA (0.52) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27691977 | 0.80 | MEN1 (0.43) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27691975 | 0.80 | MEN1 (0.43) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27640907 | 0.78 | KDM4E (0.37) | LMNAKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1948306-A | Fluoroquinolone-oxazolidone derivative, its preparation method and application | SHANGHAI MEDICINE INDUSTRY INS (CN) | 2007-04-18 | — | — | CN | disclosed |
| CN-87103138-A | New quinoline and preparation method thereof | — | 1987-11-04 | — | — | CN | disclosed |
| CN-87101731-A | Carbostyril carboxylic acid derivatives that replaces on No. 8 positions and preparation method thereof | — | 1987-09-16 | — | — | CN | disclosed |