Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27670601 | 0.87 | HTT (0.41) | TSHRNPSR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28762091 | 0.86 | MEN1 (0.43) | TSHRNPSR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5473951 | 0.82 | LMNA (0.53) | TSHRNPSR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5474300 | 0.80 | TSHR (0.41) | TSHRNPSR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27700112 | 0.74 | NEK2 (0.35) | TSHRNPSR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5707141 | 0.71 | HTT (0.41) | TSHRNPSR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5477311 | 0.70 | LMNA (0.50) | NPSR1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5475623 | 0.69 | LMNA (0.57) | NPSR1ALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL5475186 | 0.69 | HTT (0.47) | TSHRNPSR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5475680 | 0.68 | LMNA (0.56) | NPSR1ALDH1A1LMNASMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1942188-A | Pyrimidine derivatives and their use as agricultural and horticultural fungicides | BAYER CROPSCIENCE AG (DE) | 2007-04-04 | — | — | CN | disclosed |