Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29308168 | 0.83 | NR1H2 (0.43) | DPP4ARG1NR1H2 | |
| SCHEMBL934839 | 0.83 | NR1H2 (0.43) | DPP4ARG1NR1H2 | |
| SCHEMBL17715141 | 0.83 | NR1H2 (0.43) | DPP4ARG1NR1H2 | |
| SCHEMBL17715154 | 0.83 | NR1H2 (0.43) | DPP4ARG1NR1H2 | |
| SCHEMBL27600115 | 0.81 | ARG1 (0.34) | DPP4ARG1NR1H2 | |
| SCHEMBL16797265 | 0.81 | ARG1 (0.34) | DPP4ARG1NR1H2 | |
| SCHEMBL27418796 | 0.80 | DPP4 (0.44) | DPP4ARG1NR1H2 | |
| SCHEMBL6110183 | 0.77 | KMT2A (0.34) | DPP4ARG1NR1H2 | |
| SCHEMBL27618648 | 0.75 | ARG1 (0.33) | ARG1 | |
| SCHEMBL25930148 | 0.74 | CTSC (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101456841-B | Amide derivative and medicine | NIPPON SHINYAKU CO LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-100526298-C | Amide derivative and pharmaceutical | NIPPON SHINYAKU CO LTD (JP) | 2009-08-12 | — | — | CN | disclosed |
| CN-101456841-A | Amide derivative and medicine | NIPPON SHINYAKU CO LTD (JP) | 2009-06-17 | — | — | CN | disclosed |
| CN-1898208-A | Amide derivative and pharmaceutical | NIPPON SHINYAKU CO LTD (JP) | 2007-01-17 | — | — | CN | disclosed |