Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22167 | 0.95 | CA2 (0.59) | CA2CYP3A4TSHRTDP1ATM | |
| Methacrylic Acid SCHEMBL5476361 | 0.93 | CA2 (0.47) | CA2CYP3A4TSHRTDP1ATM | |
| SCHEMBL1515002 | 0.92 | CA2 (0.56) | CA2CYP3A4TSHRTDP1ATM | |
| SCHEMBL4634494 | 0.90 | CA2 (0.54) | CA2CYP3A4TSHRTDP1ATM | |
| SCHEMBL7065837 | 0.90 | CA2 (0.54) | CA2CYP3A4TSHRTDP1ATM | |
| SCHEMBL10596126 | 0.90 | CA2 (0.53) | CA2CYP3A4TSHRTDP1ATM | |
| SCHEMBL9562805 | 0.89 | CA2 (0.53) | CA2CYP3A4TSHRTDP1ATM | |
| SCHEMBL7775342 | 0.89 | CA2 (0.53) | CA2CYP3A4TSHRTDP1ATM | |
| SCHEMBL14973425 | 0.89 | CA2 (0.53) | CA2CYP3A4TSHRTDP1ATM | |
| SCHEMBL6246889 | 0.89 | CA2 (0.53) | CA2CYP3A4TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569013-B1 | Curable composition for optical parts | NIPPON CATALYTIC CHEM IND (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-0209597-A1 | EXTENDED-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1987-01-28 | — | — | EP | disclosed |
| WO-1986004343-A1 | EXTENDED-WEAR LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | disclosed |