Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874966 | 0.83 | KDM4E (0.49) | KDM4EMAPTRETHTTALDH1A1 | |
| SCHEMBL27673143 | 0.82 | RET (0.60) | KDM4EMAPTRETHTTALDH1A1 | |
| SCHEMBL3873231 | 0.80 | KDM4E (0.55) | KDM4EMAPTRETALDH1A1KEAP1 | |
| SCHEMBL27673102 | 0.80 | KDM4E (0.47) | KDM4EMAPTRETHTTALDH1A1 | |
| SCHEMBL27653184 | 0.79 | KDM4E (0.46) | KDM4EMAPTRETHTTALDH1A1 | |
| SCHEMBL27653133 | 0.79 | MAPT (0.61) | KDM4EMAPTRETHTTALDH1A1 | |
| SCHEMBL28762589 | 0.78 | HSP90AA1 (0.47) | KDM4EMAPTRETHTTALDH1A1 | |
| SCHEMBL27653103 | 0.78 | MAPT (0.50) | KDM4EMAPTRETHTTALDH1A1 | |
| SCHEMBL27673141 | 0.77 | IDO1 (0.49) | KDM4EMAPTHTTALDH1A1KMT2A | |
| SCHEMBL27653159 | 0.77 | MAPT (0.49) | KDM4EMAPTHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |