SCHEMBL27673102

SCHEMBL27673102

Cc1cc(-c2ccccc2O)c2c3ccccc3n(C)c2c1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
MAPT P10636 3/20 0.47
ALKBH5 Q6P6C2 1/20 0.41
FTO Q9C0B1 1/20 0.41
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
RET P07949 1/20 0.40
NQO2 P16083 1/20 0.40
HTT P42858 2/20 0.40
GABRP O00591 3/20 0.36
GABRD O14764 3/20 0.36
GABRA1 P14867 3/20 0.36
GABRB1 P18505 3/20 0.36
GABRG2 P18507 3/20 0.36
GABRB3 P28472 3/20 0.36
GABRA5 P31644 3/20 0.36
GABRA3 P34903 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3874031 0.85 KDM4E (0.53) KDM4EMAPTALKBH5FTOALDH1A1
SCHEMBL27673100 0.83 RET (0.56) KDM4EMAPTALKBH5FTOALDH1A1
SCHEMBL27673146 0.80 KDM4E (0.43) KDM4EMAPTALKBH5FTOALDH1A1
SCHEMBL27653184 0.78 KDM4E (0.46) KDM4EMAPTALKBH5FTOALDH1A1
SCHEMBL27653212 0.77 MAPT (0.46) KDM4EMAPTALDH1A1HPGDMEN1
SCHEMBL28762589 0.75 HSP90AA1 (0.47) KDM4EMAPTALKBH5FTOALDH1A1
SCHEMBL27653103 0.75 MAPT (0.50) KDM4EMAPTALDH1A1HPGDMEN1
SCHEMBL27673156 0.74 KDM4E (0.43) KDM4EMAPTALKBH5FTOALDH1A1
SCHEMBL3877123 0.73 KDM4E (0.56) KDM4EMAPTALKBH5FTOALDH1A1
SCHEMBL27653133 0.72 MAPT (0.61) KDM4EMAPTALKBH5FTOALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1937994-A Keratin dyeing compounds, keratin dyeing compositions containing them and their use PROCTER & GAMBLE (US) 2007-03-28 CN disclosed