Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 14/20 | 0.62 |
| ▸ | MGLL | Q99685 | 3/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2765885 | 0.94 | MLNR (0.65) | MLNRMGLLCCR1CCR3 | |
| SCHEMBL2765421 | 0.92 | MLNR (0.73) | MLNRMGLLCCR1 | |
| SCHEMBL2765627 | 0.91 | MLNR (0.61) | MLNRMGLLCCR1 | |
| SCHEMBL3567358 | 0.90 | MLNR (0.58) | MLNRMGLLCCR1 | |
| SCHEMBL2766758 | 0.87 | MLNR (0.58) | MLNRMGLLCCR1 | |
| SCHEMBL2766514 | 0.85 | MLNR (0.84) | MLNR | |
| SCHEMBL2766234 | 0.85 | MLNR (0.74) | MLNRMGLLCCR1 | |
| SCHEMBL2768337 | 0.85 | MLNR (0.57) | MLNRMGLLCCR1 | |
| SCHEMBL2767206 | 0.84 | MLNR (0.61) | MLNRMGLLCCR1 | |
| SCHEMBL2767224 | 0.84 | MLNR (0.75) | MLNRMGLLCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041093-B1 | PIPERAZINYL DERIVATIVES USEFUL IN THE TREATMENT OF GPR38 RECEPTOR MEDIATED DISEASES | GLAXO GROUP LTD (GB) | 2010-04-21 | — | — | EP | disclosed |