Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.61 |
| ▸ | DRD3 | P35462 | 6/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.61 |
| ▸ | DRD1 | P21728 | 5/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.61 |
| ▸ | HTR1A | P08908 | 4/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.61 |
| ▸ | BCL2 | P10415 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | HRH1 | P35367 | 5/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554453 | 1.00 | KCNH2 (0.61) | KCNH2CHRM2ADRA2AADRA1ADRD3 | |
| SCHEMBL27624987 | 1.00 | KCNH2 (0.61) | KCNH2CHRM2ADRA2AADRA1ADRD3 | |
| SCHEMBL27673539 | 0.86 | LMNA (0.72) | KCNH2CHRM2ADRA2AADRA1ADRD3 | |
| SCHEMBL1137922 | 0.85 | KCNH2 (0.59) | KCNH2CHRM2ADRA2AADRA1ADRD3 | |
| SCHEMBL3139347 | 0.85 | DRD3 (0.59) | KCNH2CHRM2ADRA2AADRA1ADRD3 | |
| Clocinizine SCHEMBL30363 | 0.85 | LMNA (0.84) | KCNH2CHRM2ADRA2AADRA1ADRD3 | |
| Clocinizine SCHEMBL2193158 | 0.85 | LMNA (0.84) | KCNH2CHRM2ADRA2AADRA1ADRD3 | |
| SCHEMBL1137918 | 0.85 | KCNH2 (0.59) | KCNH2CHRM2ADRA2AADRA1ADRD3 | |
| SCHEMBL1138175 | 0.85 | DRD3 (0.59) | KCNH2CHRM2ADRA2AADRA1ADRD3 | |
| SCHEMBL1138520 | 0.85 | KCNH2 (0.59) | KCNH2CHRM2ADRA2AADRA1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100340551-C | 4- (diarylmethyl) -1-piperazinyl derivatives | SUN PHARMACEUTICAL IND LTD (IN) | 2007-10-03 | — | — | CN | claimed |