Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.55 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981381 | 0.88 | HRH4 (0.62) | HRH4CDK2CDK1ADORA2AADORA1 | |
| SCHEMBL5439307 | 0.81 | IKBKB (0.58) | HRH4CDK2CDK1HRH3IKBKB | |
| SCHEMBL6979605 | 0.74 | DRD2 (0.59) | HRH4CDK2CDK1ADORA2AADORA1 | |
| SCHEMBL6976152 | 0.73 | HRH4 (0.57) | HRH4CDK2CDK1DRD2DRD4 | |
| SCHEMBL13490451 | 0.72 | MEN1 (0.55) | MEN1KMT2AHPGDSGABRA1GABRB2 | |
| SCHEMBL6968638 | 0.71 | KMT2A (0.57) | HRH4CDK2CDK1MAPTMEN1 | |
| SCHEMBL5750484 | 0.71 | CDK1 (0.43) | HRH4CDK2CDK1ADORA2AADORA1 | |
| SCHEMBL5426575 | 0.70 | IKBKB (0.67) | HRH4CDK2CDK1IKBKB | |
| SCHEMBL13724266 | 0.70 | HTR2A (0.48) | ALDH1A1HSD17B10HRH1GABRA1GABRB2 | |
| SCHEMBL13257214 | 0.69 | HRH4 (0.70) | HRH4CDK2CDK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1942463-A | 2-aminopyridine derivative | ASTELLAS PHARMA INC (JP) | 2007-04-04 | — | — | CN | claimed |
| CN-1942463-A | 2-aminopyridine derivative | ASTELLAS PHARMA INC (JP) | 2007-04-04 | — | — | CN | disclosed |