Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2766277 | 0.90 | LMNA (0.43) | TP53POLBLMNAFPR2 | |
| SCHEMBL3290063 | 0.87 | LMNA (0.50) | TP53POLBLMNAFPR2 | |
| SCHEMBL2766178 | 0.84 | LMNA (0.41) | TP53POLBLMNAFPR2GFER | |
| SCHEMBL2765742 | 0.84 | TP53 (0.41) | TP53POLBLMNAGFERKMT2A | |
| SCHEMBL2766128 | 0.80 | LMNA (0.51) | TP53POLBLMNAMAPT | |
| SCHEMBL3285238 | 0.78 | TP53 (0.52) | TP53LMNAMAPT | |
| SCHEMBL3290069 | 0.78 | LMNA (0.58) | TP53POLBLMNAMAPT | |
| SCHEMBL13376561 | 0.77 | LMNA (0.52) | TP53POLBLMNAMAPT | |
| SCHEMBL5264221 | 0.76 | TP53 (0.41) | TP53POLBLMNAGFERKMT2A | |
| SCHEMBL2767374 | 0.76 | LMNA (0.59) | TP53POLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858890-B1 | NOVEL ANTITHROMBOTIC SUBSTITUTED PYRROLIDINONES, THE PRODUCTION AND USE THEREOF IN THE FORM OF MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2010-04-14 | — | — | EP | disclosed |